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Title   기관에 침윤된 갑상선암의 치료에 대한 평가 ( Assessment of Management for Thyroid Carcinoma Invading the Trachea )
Publicationinfo   1991 Jan; 023(04): 777-783.
Key_word   Thyroid carcinoma, Tracheal invasion
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Abstract   Twenty-two patients with tracheal invasion (3 intraluminal and 19 cartilage invasion only) were seen among the total of 432 patients with thyroid carcinoma from January 1979 to Decem- ber 1988. The patients population consisted of 7 men and 15 women, with a mean age of 56.5(range 23 to 74 years). Fifeen had primary and 7 had recurrence cases. Surgical treatments for the tracheal lesion were as follows: shave the tumor off the trachea in 18 cases; window resection in 2 cases; cirumferential resection and end-to-end anastomosis in l case; and wedge resection in 1 case. Histologically, the tumors were classified as papillary cacinoma (18 cases), follicular carcino- ma (2 cases), medullary carcinoma (1 case) and anaplastic carcinoma(1 case). All patients recieved additional treatment in postoperative period. Radioactive iodine (30 to 200 mCi) was used in 15 patinets and external radiotherapy (4500 to 6000 cGy) was given to the 7 remaining patients. Lifelong thyroid hormone replacement therapy was instituted in all patients. Postoperative follow-up, excluding one patient lost to follow-up, averaged 52.5 months(range 2 to 107 months). Of these 21 patients, 14 were alive at the time of this report: but only 5 were free of disease, 7 were alive with local recurrence, and 2 were alive with local recurrence and distant metastasis. Seven patients eventually died from the disease. On the basis of this limited study we feel that a more extensive resection than shaving the cartilage should be considered at the time of initial surgery for those patients with tracheal in- vasion, even with cartilage invasion only to increase disease-free survival rate.
저 자   민진식(Jin Sik Min),박정수(Cheong Soo Park),한호용(Ho Yang Han)